I am dealing with prolonged middle of the night insomnia...for many years but it progressively has gotten worse. I have done all the usual non-medication approaches and when done strictly it helps to some degree but not enough. Lack of sleep does seem connected with stress as it is much worse during travel and when I know i have to get up early. I have talked with my doctor about anti-depressants but my experience is that when I get a good night s sleep my mood is much, much better so I am still looking to address the sleep issue first. Unfortunately, most sleep medications appear to address going to sleep, which is not my problem. Is there no safe reliable medication for chronic middle of the night awakening?